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Common adverse effects include: Gastrointestinal Issues: Nausea, vomiting, diarrhoea, and constipation are frequently reported

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The rate of treatment discontinuation due to adverse events was comparable to what has been observed in trials of GLP-1 monotherapy

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demonstrated that sickle cell anemia correlates with elevated eryptosis markers, such as PS externalization, increased ROS within RBCs, and elevated intracellular calcium levels