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To address these limitations, engineered nanozymes have emerged as a promising solution, since the concept was first proposed by Yans research team in 2007, sparking widespread interest in nanomaterial-based artificial enzymes[16]

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These combined approaches offer promising prospects for clinical implementation, and there is a pressing need to develop a comprehensive three-dimensional intervention system that integrates strain tracking, dynamic immune monitoring, and predictive analytics driven by artificial intelligence (190)