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(PubMed) Camarena V, Wang G
Exenatide and liraglutide promote neuronal survival and attenuate neuroinflammation via PI3K/Akt signaling, inhibiting apoptosis by modulating Bax, caspase-3, and Bcl-2 [9,24]
& Poole, L
This pathway activation enables: Enhanced neuronal survival under stress conditions Increased dendritic arborization and synaptic density Improved axonal sprouting and regeneration Activation of neuronal repair mechanisms Studies using neuronal cell cultures revealed that Cerebrolysin significantly increases neurite outgrowth and protects against excitotoxic injury, effects attributed to neurotrophic factor-like activities[2]
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