Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis
The primary outcomes were the percentage weight change and the proportion of participants losing at least 5% of their baseline weight, using treatment-policy estimand analysis (intention-to-treat principle)
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In recent years, the gut-brain-kidney axis has emerged as a compelling framework for understanding the interconnected pathophysiology of CKD
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doi: 10.1186/s12933-021-01366-8 88 LeeMMYKristensenSLGersteinHCMcMurrayJJVSattarN