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Reduced Inflammation and Oxidative Stress GLP1 has anti-inflammatory effects that can decrease oxidative stress in the body, which is beneficial for preventing chronic diseases such as atherosclerosis, a major contributor to cardiovascular issues

doi: 10.1016/j.neuropharm.2025.110299 109 PfausJGShadiackAVan SoestTTseMMolinoffP

The rate-limiting step of the salvage pathway is catalyzed by NAMPT and requires PRPP as a cosubstrate, which is mostly supplied by the PPP pathway in cancer cells

Further incretin-based drug development For both GIP and GLP-1, positive effects were also observed on cardiovascular complications [23], indicating a therapeutic potential beyond the improvement of diabetes complications