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This effect is consistent across the GLP-1 RA class and is generally not clinically significant, though it should be monitored in patients with arrhythmias

doi: 10.3389/fnmol.2017.00033 Received 29 September 2016 Accepted 27 January 2017 Published 13 February 2017 Volume 10 - 2017 Edited by Ildik Rcz, University of Bonn, Germany Reviewed by Wei Chen, Beijing Institute of Pharmacology and Toxicology, China

Because these drugs target separate metabolic pathways, they complement each other without directly competing for the same biological action

The injection is simple to perform and targets the fatty tissue just beneath the skin

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NDI1 expression did not have any major effects on gene expression in brown adipose fat (BAT) and iWAT (Extended Data Fig