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In sharp contrast, 5 out of 6 domains of HGF I, including N, K1, K2, K3, and SPH domains, make direct contacts with either c-MET I-SEMA or c-MET II-SEMA, burying 61, 1141, 509, 665, and 962 2 surface area, respectively
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The significant increase in basal respiration and maximal respiration 14 d pi indicates an enhanced activity of the electron transport chain, potentially reflecting a higher energetic demand and mitochondrial adaptation
In ABCC transporters, such regulatory elements are evolutionary additions to the canonical ABC exporter fold composed of two transmembrane domains (TMDs) and two nucleotide-binding domains (NBDs) (Fig
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HFD impairs liver glutathione biosynthesis, vitamin D metabolism genes and genes associated with non-alcoholic fatty liver disease (NAFLD) Genes involved in the GSH biosynthesis pathway were significantly downregulated in the livers of mice fed an HFD compared to those of mice fed a healthy diet (controls) (Fig
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