Some are unwilling to budge and allow treatment even when faced with a tearful patient on their knees begging for treatment
Longer infusions provided over the course of several days may provide longer lasting benefits opposed to a single infusion or shorter duration infusions
Repletion of vitamin B12 may improve response in patients resistant to antidepressants (10) , and in older adults with major depression, long-term supplementation with a combination of B12, B6, and folic acid enhanced antidepressant treatment efficacy (40)
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B-12 is derived from diet, particularly milk, eggs, and meat