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Both are contraindicated in personal or family history of medullary thyroid carcinoma and MEN2
True tolerance requiring dose increases happens in a small percentage of patients but isnt the norm
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Protein also helps preserve muscle mass, which is a highly relevant concern for GLP-1 users in steep caloric deficits
Mechanism of action: Activates GLP-1 receptors in the brain, gut, and pancreas Reduces appetite and food cravings Slows gastric emptying you feel full longer Stimulates insulin release, suppresses glucagon Improves blood sugar regulation FDA-approved brand names: Wegovy 2.4mg weekly, approved for chronic weight management Ozempic approved for type 2 diabetes
As a result, other drugmakers are working on generic versions
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