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Ann Pharmacother

Additionally, the symptoms a person experiences can change, disappear, and reappear over time

A provider can help shape a plan that respects your goals, other wellness habits, and how your body responds over time

doi:10.1146/annurev.nu.05.070185.000555

Safety Concerns, Risks, and Regulatory Status in the UK Neither compound is licensed in the UK

These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance