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Deoxycholic acid activates colonic afferent nerves via 5-HT3 receptor-dependent and -independent mechanisms

5 It's estimated that 9 in 10 Canadians have at least one risk factor for stroke, heart disease, or vascular cognitive impairment including: sex, age, diabetes, family history and Indigenous, South Asian and African family heritage

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In laboratory testing, tirzepatide binds to the GIP receptor with affinity comparable to native GIP itself, but its GLP-1 receptor affinity is roughly five times lower than native GLP-1

Its less about managing the symptoms of aging and more about addressing the process at a cellular level

The results reveal that a seismic shift is underway