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Signs that warrant evaluation include: pain radiating down the arm or leg persistent numbness muscle weakness worsening symptoms over time Imaging and a physical examination help determine the underlying cause of the problem

Exclusion criteria: Adults with diabetes, hemoglobin A1C 6.5%, history of chronic pancreatitis, acute pancreatitis within 180 days, previous surgical obesity treatment, use of antiobesity medication within 90 days 1961 participants randomized 2:1 to intervention versus placebo Baseline characteristics: 74.1% female, 75.1% white

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The medicine is dispensed at a 503A or 503B licensed pharmacy

Together, these peptides might improve circulation, reduce inflammation, and speed up cellular responses that allow injured tissues to develop new structures more efficiently