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A dynamic balance is maintained between the synthesis, consumption, and transport of GSH, all of which determine its intracellular concentration

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These observations dispelled the myth of good cholesterol, and the HDL-C concentration is not used in the assessment of cardiovascular risk, or as a goal of treatment of dyslipidaemia

His reasoning was elegant: if he could identify hormone-like compounds in animals with unusual metabolic adaptations, those molecules might reveal something about human physiologyor even become therapeutic agents themselves