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A 2025 systematic review in the International Journal of Dermatology documented liver function abnormalities in approximately half of IV-treated participants at high doses, which is why DermaVue restricts treatment to evidence-based clinical doses of 400 to 1200 mg with mandatory hepatic monitoring
10.3389/fimmu.2019.01328 74 LiuS
In the early phase (1 h post-administration), NR is rapidly absorbed by the small intestine and enters salvage 127
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References Scott JM, Molloy AM
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