Microdosing refers to the practice of using significantly lower doses than those officially recommendedoften a fraction of the standard starting dose
The route of administration matters
Given the established clinical use of GLP-1RAs for the treatment of T2DM, preclinical and clinical research was centered largely around DR, which suggested the neuropathologic protective effects of GLP-1 are due to downregulation of NF-B, proinflammatory cytokines such as TNF-alpha and IL-1beta, and VEGF
Ozempic (semaglutide) is FDA-approved for type 2 diabetes, not obesity or weight management
These findings have led to a growing number of Ozempic lawsuits, Mounjaro lawsuits, Wegovy lawsuits and other GLP-1 claims being filed over the past few years, each indicating that in the drug makers rush to promote the benefits associated with the treatments, they failed to adequately disclose potentially serious side effects some users experience
Users start with a low dose of these medications and gradually increase it over time until they reach a targeted dose
