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Third, discuss monitoring
1,6 The most common adverse events for this study were chromaturia (n=6), pink or red skin discoloration (n=4), hypertension (n=3), erythema (n=2), and increased blood pressure (n=2)
Although there were differences in magnitude of DMSO effect between tissue types, the affected biological processes by DMSO do not appear to be tissue-specific
Vectors were digested using enzymatic restriction digest and ligated to either gel-purified PCR products or ordered gene fragments using Gibson assembly
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The K-F ring is present in the vast majority of Wilsons patients who present with neurologic symptoms with few exceptions (about 5%).22 Children with Wilsons generally present with hepatic symptoms initially, and therefore rarely have K-F rings
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