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Statistical methods were not used to chose sample sizes

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1 When IGF-1 binds to IGF-1R, the tyrosine kinase activates the phosphoinositide 3-kinase (PI3K)-AKT pathway and many integral proteins involved in cellular metabolism, apoptosis, cell adhesion, and angiogenesis are regulated within this pathway

Nature Reviews Microbiology, 19 (1), 5571

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