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Estimates of the effects of SGLT2is and GLP-1 RAs on cardiovascular and kidney disease and all-cause mortality were assumed to be class effects and were thus drawn from the recent meta-analyses of major-outcomes trials [2,3,4]

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According to Reuters, the U.S

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Effects of tirzepatide on body weight GLP-1 receptor agonists, initially developed and marketed to exploit their relevant hypoglycemic effects, have shown positive but heterogeneous effects on body weight control