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The focus of this review is the role of factors originating from the alpha cell in the regulation of beta cell activity and, by extension, the regulation of glucose homeostasis

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Additionally, structural refinement reduces interaction with non-target receptors that regulate hormones such as cortisol or prolactin

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Furthermore, the KO rats showed increased adipocyte maturation by increased expression of genes involved in triglyceride uptake and in PPAR expression and increased adiponectin and leptin levels

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