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Acknowledgements The authors would like to appreciate the facilitation of experimentation at Applied Sciences Private University, Jordan and Princess Nourah bint Abdulrahman University, Saudi Arabia

282,283 These cells accumulate in the synovial membrane and subchondral bone, releasing pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which promote the degradation of joint cartilage and the inflammatory response

Initial positive results may emerge within weeks, marking semaglutide treatment as a holistic health-enhancing endeavor

Eur J Pharmacol (2015) 768:217

It is important to emphasize the distinction between promising rodent studies and clinical relevance in humans