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The majority of studies have focused on the effect of GLP-1R activation on the mesolimbic pathway

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Dose adjustment, protocol modification, or reevaluation of injury severity and type may be appropriate

Given the differences in follow-up times, the concordance in weight loss outcomes between many of these prior studies and the current real-world study reinforces the potential of semaglutide 2.4 mg and tirzepatide as effective treatments for obesity

- (Wegovy), (Ozempic) (Novo Nordisk) GLP-1