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Our registration number is INPLASY2023110057 Our DOI number is We followed the Preferred Reporting Items for Systematic Evaluations and Meta-Analyses (PRISMA) statement and the Cochrane Collaboration ( recommendations on reporting preferences

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In cases of chronic malabsorption, replacement therapy is needed with variable doses (50500 mg/day according to serum concentration) (78)

OFAs decision to file an appeal introduces a second legal front, raising the possibility of an extended legal fight with no immediate relief for compounders or patients

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It is produced by the pharmaceutical company Novo Nordisk