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The genetic test does not predict exact medication response or guarantee outcomes, but it can support a more informed conversation with a qualified healthcare provider about why a patient may be experiencing a plateau or tolerability issues on a single GLP-1 agent

Overall, the use of metformin as an adjunct treatment for AN, particularly in patients with underlying hyperglycemia, is supported in the literature, but further studies are needed to clarify dosing, duration of therapy, and patient populations that will benefit most from adding metformin to their treatment regimens

1429, Westenhoefer, Joachim, et al

Elimination : Metabolites are cleared in the feces and urine

The retatrutide dosage chart provides additional context on how these doses translate to clinical outcomes

When I first started taking the drug, I was reluctant to mention it to anyone