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As lean mass increases and fat decreases at the same time, the scale may stay flat even while body composition improves

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Thats a MASSIVE difference

It enhances glucose-dependent insulin secretion (meaning it prompts insulin release primarily when blood sugar is elevated), slows gastric emptying so a meal leaves the stomach more gradually, and acts on appetite centers in the brain to promote a feeling of fullness

In contrast, microsatellite-stable CRC tumors, representing most cases, are less immunogenic and pose a greater challenge for immunotherapy