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As the lungs expand with the first breath, the pulmonary resistance drops significantly and the pulmonary flow increases

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After 25 min of intranasal delivery, relatively high levels of DFO were found in the frontal cortex (2.14.7 M) and hippocampus (1 M), higher than those in peripheral areas (kidney 0.63 M, liver 0.37 M) (Hanson et al., 2009)

Zu bemerken ist, dass diese Patienten aufgrund ihrer Grundkrankheit oder der Vortherapie bereits Risikopatienten sind