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Gastrointestinal issues are usually strongest in first-time users, or when people step up to a larger dosage, but they usually dissipate over time

Rubin, R

Quieting "Food Noise": How GLP-1s and Mindfulness Rewire the Default Mode Network (DMN) and Reward Circuits

Consider switching to a non-oral contraceptive method (such as an IUD, patch, or implant), or use an additional barrier method (such as condoms) for at least 4 weeks after starting semaglutide and for at least 4 weeks after each dose increase

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