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The inhibition of the GPX3 gene leads to a decrease in the ability of tumor cells to survive without anchorage and a reduced capacity to respond to external oxidative stress

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One recent study reported that depletion of glutathione (GSH) contributes to protein homeostasis and cell survival in tumors through deubiquitinating enzymes ( Potential confounding factors, limited sample sizes, and other biases in observational studies make it difficult to derive an undetermined causal conclusion between antioxidants and cancers

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