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Its simultaneous action on GIP receptors further amplifies insulin secretion in response to food, while potentially improving the body's ability to utilize fat as fuel
showed that the activation of GLP-1R by liraglutide led to an anti-tumor effect on human pancreatic cancer via the inhibition of the PI3K/AKT pathway (224)
It is expected to become a new target for the treatment of metabolic disorders
Nadkarni P, Chepurny OG, and Holz GG
Preclinical studies have shown that GIP may reduce body weight by reducing food intake and increasing energy consumption, and in combination with GLP-1 receptor agonists, may have a greater effect on patients' blood glucose and body weight
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