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It can be noted that a vitamin B12 deficiency reduces platelets, but when the deficiency is corrected with B12 injections, platelets would be expected to rise (to normal levels)

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May relate to blood pressure effects

bioRxiv , 2023.2010.2023.563621 (2023)

If you simultaneously reduce dose, change injection timing, and switch sources, you will not know which change helped

However, they work best when combined with a healthy diet and exercise routine