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Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid: potentiation by low-level depolarization

Ha JH, Kim JE, Kim YS

Genetic Factors That Influence How Quickly Semaglutide Works for You Individual variation in semaglutide response is partly driven by genetic differences in GLP-1 receptor function and related appetite-regulation pathways

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The LEADER trial specifically tracked cardiovascular outcomes in 9,340 patients and found that semaglutide reduced the composite risk of major adverse cardiovascular events by 26%, with blood pressure improvements representing one contributing factor