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[10]Risk Assessment for L-Arginine PubMed View source L-Citrulline: 3 to 5 grams of pure L-citrulline, or 6 to 8 grams of citrulline malate (which contains roughly 3.5 grams of actual citrulline in the 2:1 malate form)

It is the primary driver of autoimmune diseases like Hashimotos Thyroiditis

Studies confirm that hormonal shifts during perimenopause and menopause contribute to increased abdominal fat, insulin resistance, and slower metabolism

Enzymes involved in L-carnitine biosynthesis are expressed by small intestinal enterocytes in mice: implications for gut health

A 180-pound individual should target 125 to 180 grams daily

PMID 1980860