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gastrointestinal effects (nausea, vomiting, diarrhea) are most common during dose escalation

doi: 10.3390/nu12071987

NEJM (2025): Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity

How Semaglutide Works and Why Kidney Function Matters Semaglutide belongs to a class of drugs known as GLP-1 receptor agonists, which help regulate blood sugar by mimicking a hormone called glucagon-like peptide-1 (GLP-1)

What you actually spend hinges on coverage, the indication written on your prescription, savings-program eligibility, pharmacy choice, and whether a licensed compounded pathway applies