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The therapeutic effect of GLP-1 on MASH is thought to be due to a reduction in body weight caused by a decrease in appetite and insulin resistance, which leads to an improvement in dyslipidemia and hepatic inflammation 33,34
doi: 10.1111/j.1463-5224.2006.00462.x
In this scenario, the risk-benefit discussion is the standard one, plus the additional considerations around muscle loss and bone health that weve covered above
According to Novo Nordisk and the FDA website, Novo Nordisk is the only company in the U.S
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