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10.1038/s41586-018-0119-x Nature 160 RothhammerV.MascanfroniI
A trial with Mediterranean mussels showed that high Cu2+ concentrations led to valve closure and a decreased heart rate in mussels (55)
Responses are measured on a scale of 1 to 5, with 5 being the best score
Genes linked to tissue destruction and fibrosis are suppressed
Viscosity is a critical quality attribute because it directly affects pump performance (higher viscosity requires more force to actuate), valve function, and droplet size distribution (more viscous formulations tend to produce larger droplets with reduced aerosol fineness)
Not Tested On Animals
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