Despite the benefits of GLP-1 RAs, they are not commonly prescribed in people living with T2DM and CKD
doi:10.1530/EJE-14-0147 Adlin V
Additionally, GIP directly stimulates lipogenesis, while GLP-1 indirectly promotes lipolysis, collectively maintaining healthy adipocytes, reducing ectopic fat distribution, and increasing the production and secretion of adiponectin from adipocytes
I'm on a stimulant medication for ADHD and I'm wondering if it's the stimulating aspect alone that's causing the reduction in positive benefits
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While multi-agonism with incretin hormones and glucagon has demonstrated great therapeutic potential, the conceptual approach of polypharmacology has also been extended to other hormone combinations