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If you have MTHFR mutations and previous poor response to cyanocobalamin supplements, you might prefer a formulation containing methylcobalamin instead

Yamada S, Horiguchi K, Akuzawa M, Sakamaki K, Shimomura Y, Kobayashi I, Andou Y, Yamada M

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10.1038/nrm3772 41 JangJ.WangY.KimH.-S.LalliM