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The lack of central carbon and nitrogen catabolism not only leads to energy deficiency but also reduces the supply of the main metabolite anabolic precursors such as pyruvate, acetyl-CoA, glucose-6-phosphate, and erythrose 4-phosphate used for biomass biosynthesis 21

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REM sleep is a part of the sleep cycle that usually occurs late in the night and in the early-morning hours, so if this is the time in which your child awakens, they likely were experiencing a nightmare as opposed to a night terror