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Effects of pramlintide, an amylin analogue, on gastric emptying in type 1 and 2 diabetes mellitus

Beneficial Endocrine but Adverse Exocrine Effects of Sitagliptin in the Human Islet Amyloid Polypeptide Transgenic Rat Model of Type 2 Diabetes: Interactions with Metformin

metabolized by proteolytic cleavage and subsequent beta-oxidation (Kommu & Whitfield, 2024)

The FDA approved liraglutide (Victoza) at doses of 0.6 mg, 1.2 mg, and 1.8 mg daily for T2DM patients with unsatisfactory diet or exercise control, and 2.4 mg and 3 mg as a chronic weight management drug

At the same time, a substantial proportion of uptake reflected switching from injectable AOM GLP-1-based medications, particularly AOM tirzepatide and injectable AOM semaglutide

Besides, Exendin-4 could promote the polarization of bone marrow-derived macrophages into M2 subtype (4.2 g/kg/day) (31)