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For PV3-SC8 GPP3+GSH clear structure was observed in the cryo-EM map up to the end of the C-terminus (Gln238), whereas for PV3-SC8 pleconaril+GSH only an additional two residues (Leu236 and Pro237) became ordered upon GSH binding

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However, the relationship between p53 and ferroptosis is context-dependent, with p53 sometimes exerting protective effects

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