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MEASUREMENTS: Energy expenditure and substrate oxidations were measured before and for 4 h after standard breakfast (20% of calculated daily energy requirements, 50% of energy from carbohydrates, 37% of energy from fat and 13% of energy from protein) using a ventilated hood system

In SURPASS-2, which compared tirzepatide to semaglutide 1 mg in 1,879 patients with type 2 diabetes, tirzepatide 5 mg, 10 mg, and 15 mg reduced systolic blood pressure from baseline by 5.6, 7.4, and 8.0 mmHg respectively at 40 weeks, compared to 5.3 mmHg with semaglutide

So the useful cost question is not what one dose costs

The trade-off is more injections per session and more reconstitution math

Vitamins and fatty acids against chemotherapy-induced intestinal mucositis

For more, see our discussion of fenbendazole and chemotherapy