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Eight percent weight loss, halved liver fat, lower triglycerides, and reduced appetite cannot be explained by GIP alone

A standard chow diet (RM1 (E) 801492, SDS) and tap water were provided ad libitum

Rapid weight loss increases cholesterol saturation of bile, which promotes stone formation

Several research groups have investigated its interaction with the NO system and prostaglandin pathways in digestive tissue models

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The SELECT trial (N=17,604) showed semaglutide 2.4 mg reduced major adverse cardiovascular events by 20% at a median follow-up of 34.2 months [13]