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Common side effectsnausea, vomiting, and constipationare usually dose-dependent and temporary but lead to discontinuation in 1015% of users in clinical trials

[1] [2] Gastrointestinal tolerability must be thoroughly assessed before dose advancement

It should also not be used during pregnancy or during breastfeeding

Importantly, patients considering therapy changes should consult qualified clinicians

Therefore, patients should check whether the pharmacy that will ship their medication has a physical address and a telephone number based in the U.S

These carriers have been found to have higher ALT activity, indicating damage to hepatocytes