doi: 10.1146/annurev-biochem-061516-045037 8 SchieberMChandelNS
Given that myocardial infarction is accompanied by metabolic stress and AMPK activation, it can be inferred that AMPK activation leads to PINK1-Parkin mitophagy, suggesting that mitophagy decelerates the progression of necrotic death in cardiomyocytes [108]
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Once again, the derived slope of 1.0068, which closely approximates unity, and the small intercept of 0.8758 provide emphatic confirmation of the high precision and accuracy of the GPx-Tiron method when validated against the GPx-CUPRAC reference standard
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