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Nature 477 , 482485 (2011)

10.1038/s41591-019-0495-2 106

The hyperactivation of ERK1/2 results in enhanced expression of multidrug resistance proteins (e.g., MDR1) and cyclin D1

Treats Acne and Breakouts Thanks to its anti-inflammatory and antimicrobial properties, Cica for skin can help calm active acne and reduce post-breakout redness

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