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Multivalent S2-based vaccines provide broad protection against SARS-CoV-2 variants of concern and pangolin coronaviruses

Assemble all required materials: Lyophilized peptide vial Bacteriostatic water for injection (0.9% benzyl alcohol) Sterile syringes (typically 3mL for reconstitution) Alcohol prep pads Sharps disposal container Pro tip: Never use distilled water or sterile water without preservatives for multi-dose peptide vials

An intermediate goal has been to develop vaccines against a subset of these viruses, referred to as broadly protective coronavirus vaccines rather than pan- or universal vaccines

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