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Wound Healing, Skin Repair, and Regeneration Research A multicenter, randomized, evaluator-blinded, placebo-controlled study in diabetic neuropathic ulcers reported greater median plantar-ulcer closure with topical glycyl-L-histidyl-L-lysine copper gel compared with vehicle, 98.5% versus 60.8%, and lower ulcer infection incidence, 7% versus 34% [3]

Especially in embryonic and differentiation settings, iron availability significantly affects the determination of macrophage destiny and functional programming