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Raw materials, cleanroom manufacturing, fill-finish, and quality testing set that floor well above the $3-5 price point that characterizes the lowest-tier marketplace listings

While the more obvious route would be directly suppressing TNF, that might not be a good idea because of its important roles in fighting infections and other invaders, which is already a concern for current treatments, they say

Accurate diagnosis through physical exams, imaging, and nerve conduction studies determines the most effective treatment path

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Agricultural and Biological Chemistry, 55 (10), 2585-2590.