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Peroxiredoxin (Prx) 3, a cysteine-dependent peroxidase enzyme, is also present in the mitochondria, whereas Prx5 can also be found in the cytosol, in peroxisomes, and in the nucleus [28]

doi: 10.1210/jc.2014-4560 146 DelivanisDAGustafsonMPBornschleglSMertenMMKottschadeLWithersSet al

Functional muscle recovery with nanoparticle-directed M2 macrophage polarization in mice

Expression of methylthioadenosine phosphorylase cDNA in p16-, MTAP- malignant cells: restoration of methylthioadenosine phosphorylase-dependent salvage pathways and alterations of sensitivity to inhibitors of purine de novo synthesis

When RNA therapeutics are applied in the brain, they are usually delivered to the CNS through intrathecal injections, ensuring adequate drug levels in disease-relevant areas by circumventing the BBB (Holm et al., 2022)

Experimental Results: Bone mineral density (BMD): OVX control group: Lumbar BMD decreased by 28% and hip BMD decreased by 25% compared to Sham group (successful osteoporosis model)