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Microb Pathog 36:227236 Mantovani A, Cassatella MA, Costantini C, Jaillon S (2011) Neutrophils in the activation and regulation of innate and adaptive immunity

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The researchers thought this was due to the increased synthesis of extracellular matrix molecules such as hyaluronic acid and perhaps collagen

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The stratum corneum (outermost skin layer, about 15 to 20 micrometers thick) is a brick-and-mortar structure of dead cells embedded in a lipid matrix