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J Pediatr Urol 17:681689

However, it can be difficult to maintain these levels, especially as you get older, live under constant stress, or have an ongoing health problem

When patients present with concerning symptoms whilst taking B12 supplements, alternative diagnoses should be considered, including allergic reactions to supplement excipients, interactions with other medications, or coincidental illness

Does this change anything outside the United States

And you test that hypothesis by giving the patient that treatment, and then you see if they get better